List of notable members of the family:
Theophylaktos (Nikephoros) Botaneiates: Doukas of Thessalonike in the early 11th century, under Basil II (976‑1025). He took part in the battles against the Bulgarians of Samuel in the summer of 1014.
Michael Botaneiates: Son of the above Theophylaktos. In 1014, he distinguished himself in the battles against the Bulgarians in the area of Thessalonike. In 1021‑1022, he participated in the campaigns of Basil II against the Abkhazians.
Nikephoros Botaneiates: Son of the above. He launched a military career in the years of Constantine IX Monomachus (1042‑1055) and participated in the rebellion of Isaac Komnenos in 1057, when he was a magistros. After 1057, he held top military posts. In the 1060s he was a distinguished military commander in the Balkans and Antioch. As the strategos of the theme of Anatolikon and kouropalates he revolted in 1077 in order to occupy the throne. He ascended the throne in 1078; in 1081 he was dethroned by Alexios Komnenos in 1081 and became a monk.
Botaneiates: Grandson of Nikephoros III Botaneiates, who married the daughter of Manuel Komnenos, the brother of Alexios I, ca. 1085.
Nikephoros Botaneiates: Ca. 1110‑1112 he married Eudokia, the daughter of the sebastokrator Isaac Komnenos, the brother of Alexios I. He received the high title of sebastos.
Manuel Botaneiates: Known in the first half of the 12th century, he married Eirene Synadene. He was honoured with the title of sebastos.George Botaneiates: Known in the first half of the 12th century, he married Zoe Doukaina. He was honoured with the title of sebastos.