Middle of the 4th or possibly the beginning of the 3rd century BC: re-settlement of the citizens of Latmus in Heraclea.
Until 190 BC: Successive changes of power in Heraclea between the Seleucids and the Ptolemies.
190 BC - 129 BC: Heraclea is given free status. The first coins are issues. Financial heyday. 129 BC: Caria and Heraclea become part of the province of Asia.
297 AD: Heraclea part of the province of Caria.